Over the year, we have published three books that focus on what nurses must recognise and respond to: Neurological Examination for Nurses, Glasgow Coma Scale for Nurses, and Intracranial Pressure for Nurses. These books build practical confidence. They help nurses see, interpret, and act. But as our understanding deepened, one truth became clear: without knowing how neurons communicate, how signals travel, and how networks create thought and movement, the picture of the nervous system remains incomplete.
This book is written to complete that picture.
We begin with the neuron because it is the smallest meaningful unit of the nervous system — the equivalent of the alveolus, the nephron, or the cardiac cycle in our previous volumes. Every sensation, movement, memory, and emotion begins with the activity of this single cell. By understanding the neuron clearly, the entire nervous system becomes easier to grasp.
A deeper understanding of neurophysiology also provides a foundation for pharmacology. Every drug that affects the brain or spinal cord — from analgesics to antidepressants, antiepileptics to anaesthetics — works by influencing neurons, synapses, or neurotransmitters. Without a grasp of how signals are generated and transmitted, pharmacology can feel like a list of names and effects. With that understanding, it becomes logical and predictable. Neurophysiology turns pharmacology from memorisation into understanding.
Just as importantly, neurophysiology clarifies the aetiology of many neurological and psychiatric illnesses. When we understand how neurons fire, how synapses strengthen or weaken, and how networks coordinate activity, the causes of conditions such as Parkinson’s disease, epilepsy, depression, dementia, and neuropathic pain become far more comprehensible. Instead of memorising symptoms, nurses can see how disrupted signalling leads to clinical presentation.
Although this book builds from the neuron outward, I encourage you to read Chapter 9 and the Epilogue, even if you do not read every chapter. These final sections bring the science back to the bedside, showing how neurons, synapses, and networks translate into the patterns we assess and the people we care for. They hold the heart of this book — not because they contain the most detail, but because they reveal the meaning behind it.
Every chapter in this volume connects cellular events to clinical practice, so that nurses can see how physiology becomes pattern, and how pattern becomes understanding. If this book succeeds, it will give readers not only knowledge, but confidence: the confidence that comes from understanding what lies beneath the signs we assess every day.
This book is offered in that spirit — to illuminate, to clarify, and to support the work of nurses who care for patients with neurological conditions. It is the fourth step in a journey we have taken together, and I hope it brings the same clarity and usefulness as the books before it.
Wei Lin is a contemplative man and lifelong seeker. Now in his seventies, he has long since passed the age of recklessness. Formerly employed in the service industry, he understands the mundane realities of life yet recognizes the pure light within the heart. His hospital experience shaped his understanding of suffering, vigilance, and the quiet heroism of nurses.
In the 1980s, he briefly took monastic vows, observing the Eight Precepts and studying under Masters Baodeng, Jinshan, and Zhifan. His character remains unconventional — a free-spirited wanderer who dwells with his wife and daughter, walks with dogs, and finds companionship in half the Analects, guidance in Buddhist verses, and a mirror for the heart in chapters of military strategy.
Though his life is stable and his family harmonious, he delights in the company of ancient sages, finding solace in classical texts and inspiration without barriers. His thoughts know no fixed rules, and his writing reflects a mind that navigates its remaining years without growing old.
This booklet is one of many distillations — not just of clinical knowledge, but of a life spent listening, watching, and walking slowly through the world.