Roger A. MacKinnon, M.D., is Professor Emeritus of Clinical Psychiatry at the College of Physicians and Surgeons of Columbia University in New York, New York.Robert Michels, M.D., is Walsh McDermott University Professor of Medicine and Psychiatry at Weill Medical College of Cornell University in New York, New York.Peter J. Buckley, M.D., is Professor of Psychiatry at Albert Einstein College of Medicine of Yeshiva University in Bronx, New York.