Clinical Potential of Exosomes: Diagnostic and Therapeutic Insights

Covering a wide realm of topics on extracellular vesicles, this book provides an in-depth understanding of the multifunctionality of exosomes that has created novel opportunities for precision medicine, providing individualized strategies for the detection, therapy, and surveillance of many medical conditions. It explores the diverse roles and features exhibited by cells based on their origin, delving into the intricate mechanisms that govern exosome biogenesis and cargo loading while also shedding light on their roles as molecular couriers. The significant and diverse potential of exosomes and extracellular vesicles in the context of managing and combatting various diseases and health are discussed, such as for site-specific drug delivery and vaccine delivery; for cancer management; for the treatment of cardiovascular diseases, neurodegenerative diseases, infectious diseases, dermal ailments, and ophthalmic ailments; in reproductive medicines; and in regenerative medicines; as well as in gene therapy and personalized care. A chapter also addresses the regulatory aspects and concerns regarding exosome-based drug delivery.