miRNA in Human Disease: From Biomarkers to Therapeutics

Parul Gupta · Ravindra Kumar · Virendra Singh · Susmit Kosta · Pushpendra Singh · Vijay Pratap Singh · Shraddha Gurha

Oct 2026 · Academic Press

Ebook

220

Pages

Eligible

This book will become available on October 30, 2026. You will not be charged until it is released.

About this ebook

miRNA in Human Disease: From Biomarkers to Therapeutics explores the critical role of microRNAs (miRNAs) in the development and progression of various diseases, emphasizing their significance as biomarkers and therapeutic targets. Sections provide a comprehensive overview of the biogenesis, function, and regulation of miRNAs, offering insights into how these small noncoding RNA molecules influence gene expression and contribute to disease development and progression. The book covers traditional and advanced methods for miRNA extraction, the role of miRNAs in infectious diseases, cancer, neurological disorders, cardiovascular disease, hemoglobinopathies, pregnancy complications, and metabolic disorders.Sections also discuss the latest research on miRNA-based therapies, including the design and delivery of miRNA mimics and inhibitors and their potential applications in personalized medicine. With a strong focus on practical implementation, the book includes detailed case studies and real-world examples that demonstrate the clinical relevance of miRNA research. It addresses the challenges and future directions in the field, providing a roadmap for researchers, clinicians, and industry professionals to harness the potential of miRNAs for disease diagnosis, treatment, and prevention. - Provides a comprehensive understanding of the role of miRNAs in various diseases, including their biogenesis, function, and potential as biomarkers and therapeutic targets - Explores the latest research on miRNA-based therapies, offering insights into how these small noncoding RNA molecules can be used to develop new treatments for a wide range of diseases - Highlights practical examples and case studies that demonstrate the real-world applications of miRNA research in disease diagnosis, treatment, and personalized medicine

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About the author

Dr Parul Gupta is a research professional with a Ph.D. in Zoology and 10 years of experience in teaching and research holding a CSIR-NET certificate in life sciences. Currently, she is working as a Research Associate at ICMR-NIRTH with a strong background in scientific research, laboratory expertise, and team collaboration. She has an experience of teaching of 4 years from reputed degree college. Her skills encompass proficiency in working knowledge of molecular techniques like PCR, ELISA, gene sequencing with skills of data analysis. She has 11 publications in peer-reviewed journals and own a strong foundation in medical pharmaceutical knowledge with effective scientific writing skills. Additionally, she completed a 3-month course in Good clinical practice in clinical trials and attended several workshops and conferences. As a researcher and teacher, her theoretical as well as practical knowledge of the subject, which makes her understand the informative content of the book.Dr Ravindra Kumar is a Scientist D at ICMR-National Institute of Research in Tribal Health, Jabalpur, with expertise in Genetics and Molecular Hematology. He is PhD in genetics holding CSIR-NET, UGC-NET and GATE certificate in life sciences. Kumar has over 12 years of research and teaching experience, previously working as Scientist C and B at the same institute, and as Scientist and Head at Central Research Laboratory, Sri Aurobindo Medical College. Dr. Kumar has received numerous awards, including the "Achiever" award from Thalassemic India, Young Scientist Award under DST-Fast Track Scheme, and Research Associate Award from CSIR. He published 117 research papers in peer-reviewed journals such as Nature etc. He worked as PI of 11 projects and guided 08 MD and 06 DM students. His qualifications and experience make him a renowned expert in his field.Dr. Virendra Kumar is an Assistant Professor at Jawaharlal Nehru University's School of Biotechnology, specializing in cancer genomics and epigenomics. Holding a Ph.D. in Bio-medical Pathology, they possess extensive research experience in identifying cancer diagnostic and prognostic markers. Their work has yielded 16 international publications in esteemed journals, including Journal of Biomolecular Structure and Dynamics and Immunology Letters. A recipient of prestigious awards, such as the American Society of Human Genetics' Developing Country Award (2020) and the UGC-Dr. D.S. Kothari Postdoctoral Fellowship, Dr. Kumar has also presented their research at numerous national and international conferences. As an educator, they teach courses on oncogene research, immunology, and emerging technologies. Additionally, Dr. kumar serves as a reviewer for the journal Technology in Cancer Research & Treatment and is a member of the American Society of Human Genetics (2020-2022), demonstrating their expertise and commitment to advancing cancer research.

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