In the first part, we discuss the concepts of qk-derivative and qk-integral, and establish their basic properties. As applications, we study initial and boundary value problems of impulsive qk-difference equations and inclusions equipped with different kinds of boundary conditions. We also transform some classical integral inequalities and develop some new integral inequalities for convex functions in the context of qk-calculus. In the second part, we develop fractional quantum calculus in relation to a new qk-shifting operator and establish some existence and qk uniqueness results for initial and boundary value problems of impulsive fractional qk-difference equations.