Blood Cancer: The Genetics of Aetiology, Diagnosis and Management

Blood cancers are complex and heterogeneous, driven by chromosomal and genetic abnormalities that shape both development and clinical behaviour. Blood Cancer: The Genetics of Aetiology, Diagnosis and Management brings molecular pathology to the forefront, linking aetiology, laboratory investigation and treatment strategies across leukaemia, lymphoma and myeloma within a UK healthcare context.

Written by established writer, practitioner and researcher Andrew Blann, this text guides readers from foundational principals to applied clinical practice. Beginning with the constituents and formation of blood, it introduces key laboratory molecular pathology techniques before exploring myeloid and lymphoid malignancies in depth. Later chapters focus on diagnostic genetic markers and evolving treatment modalities, including immunotherapy, molecular therapies, and stem cell transplantation.

This integrated resource helps readers connect laboratory science with bedside decision-making, clarifying how abnormal genes and chromosomes underpin classification, prognosis and targeted therapy. Features include:

• Clear explanations of molecular pathology techniques used in modern haematology and oncology laboratories
• In-depth discussion of hallmark genetic markers such as the Philadelphia chromosome and their diagnostic significance
• Coverage of contemporary treatment approaches, from chemotherapy to advanced immunotherapies
• Richly illustrated diagrams, tables, and clinical images to simplify complex concepts

Designed for undergraduate and postgraduate students in medicine, biomedical clinical science, pathology, haematology, and oncology, Blood Cancer: The Genetics of Aetiology, Diagnosis and Management also supports advanced practitioner nurses, pharmacists, biomedical scientists, and clinicians seeking authoritative guidance on blood cancer genetics.